Metabolic phenotyping of BMI to characterize cardiometabolic risk: evidence

from large population-based cohorts.

Nature Communications (2023)14:6280

.

📌Significance :

The study highlights the crucial role of metabolic BMI (mBMI) in discerning metabolic health variations

that are not apparent through traditional BMI measurements. mBMI captures a metabolic signal

independent of BMI but closely mirrors the BMI signal. This provides an independent measure of

the metabolic dysregulation associated with obesity to assess metabolic health to identify “at-risk”

individuals for targeted intervention and monitoring.

.

📌Importance of lipidology :

The lipidomic-based models for BMI to calculate a metabolic BMI score (mBMI) can be used as a

measure of metabolic dysregulation associated with obesity.

.

📌Connectivity to other field :

This study integrated lipidomic data with anthropometric, clinical, and behavioral data to figure out

the association between metabolic BMI score and T2DM, pre-diabetes, CVD, lifestyle, and dietary

habits.

-

✏️READ MORE

https://doi.org/10.1038/s41467-023-41963-7